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Science & Innovation

BDDE Technology

J1 Global's core hyaluronic acid platform, precisely engineered for long-lasting,
natural-looking results across a wide range of treatments.

Overview Key Feautres

Key Features (LCCR Technology Advantage)

  • 01

    Low Control
    Cross Linker Process

    During the cross-linking maturation process, a minimal amount of BDDE cross-linking agent is diluted and sprayed to ensure even and complete cross-linking across all HA components. This helps create a stable gel structure while precisely controlling the use of the cross-linking agent.

  • 02

    Complete BDDE Removal
    through Micro-Trituration Process

    Through the Micro-Trituration Process, the HA cross-linked gel is finely ground and cut to shorten dialysis time and maximize stability. This process helps minimize residual BDDE and impurity residues while supporting full hydration of the HA gel.

  • 03

    Efficient
    Sterilization

    The sterilization process is optimized to minimize and streamline high-temperature exposure. This helps preserve the product’s viscoelasticity while ensuring the final product meets safety and quality standards.

J1’s Purification Technology That Minimizes Residual BDDE

Together, the Low Control Cross Linker Process, Complete BDDE Removal through Micro-Trituration Process, and Efficient Sterilization form J1’s LCCR Technology a core process developed to deliver stable, refined, and high-quality HA fillers with minimized residual BDDE and consistent product performance.